Callewaert Lab
Engineering next‑gen molecules to fine‑tune the immune response.
This lab designs and synthesizes novel peptides and small molecules that selectively enhance or suppress immune pathways. Through in vitro screening and animal models, they optimize candidates for treating autoimmune disorders and improving vaccine efficacy.
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Nico Callewaert
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Elizabeth Jones
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Boris Benno
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Francesca Neville
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Cristina Lavazza
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Frank Denver
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Darren Wilson
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Mark your calendars. We’re excited to invite you and your loved ones (family/friends) to an Open Door Day at the VIB Bio-Incubator on Het Eilandje. This is a great chance to explore the building and its offices, and food and drinks will make it even more enjoyable.
Be sure to ...
The Revolutionizing Next-Generation Sequencing conference returns for its sixth edition, uniting leading researchers to discuss the latest breakthroughs in genomics. Among them are RNGS25 OC members Bram Van den Bergh and Wouter De Coster, two VIB scientists at the forefront of sequencing technology. Their work, which ranges from tracking antibiotic ...
Leuven, 23 January 2025 – The Proof of Concept Grants by the European Research Council aim to support scientists with exploring the validation potential of their ERC-funded discoveries. This year, Prof. Max Mazzone and Prof. Peter Carmeliet (both VIB-KU Leuven VIB-KU Leuven Center for Cancer Biology) received an ERC Proof ...
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- 22-03-2025
Fight to Survive: Marchantia Synthesizes Newly Identified Metabolites in Response to Wounding.
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- 03-03-2025
Replication Stress, Microcephalic Primordial Dwarfism, and Compromised Immunity in Atrip Deficient Patients.
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- 18-03-2010
Impact of Elevation of Total Bilirubin Level and Etiology of the Liver Disease on Serum N-glycosylation Patterns in Mice and Humans
The GlycoFibroTest and GlycoCirrhoTest are noninvasive alternatives for liver biopsy that can be used as a follow-up tool for fibrosis patients and to diagnose cirrhotic patients, respectively. These tests are based on the altered N-glycosylation of total serum protein. Our aim was to investigate the impact of etiology on the alteration of N-glycosylation and whether other characteristics of liver patients could have an influence on N-glycosylation. In human liver patients, no specific alteration could be found to make a distinction according to etiological factor, although alcoholic patients had a significant higher mean value for the GlycoCirrhoTest. Undergalactosylation did (...)
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Our Research Groups
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Patient‑derived Organoid Platforms for Personalized Medicine
Using organoid cultures to predict individualized drug responses.
By growing mini‑organs from patient biopsy samples, we create high‑throughput drug screens tailored to each individual’s tumor or genetic disease. Integrated genomic and pharmacodynamic analyses will pinpoint optimal therapies. This approach seeks to streamline personalized treatment decisions in clinical settings.
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